12/12/2023 0 Comments 2d 4d ratio pubmed![]() In line with the previous individual level findings, the results suggest that prenatal sex hormone effects are sex-specifically involved in suicide and neurological conditions. The normalized female parameters showed the same cross-national correlations. In the exploratory analyses, the normalized male 2D:4D values were negatively associated with the normalized male deaths rates from communicable, maternal, perinatal, and nutritional conditions, respiratory infections, asthma, neurological conditions, and Alzheimer’s disease and other dementias. Normalized male 2D:4D correlated positively with normalized male life expectancy (at birth, r = 0.46, p = 0.029 at the age of 60, r = 0.44, p = 0.038) and negatively with normalized male suicide rates ( r = − 0.49, p = 0.017). All parameters were normalized to the national mean (of males and females) and analyzed across nations. We also used a hypothesis-free approach to investigate associations with other causes of death. Our primary aim was to verify that 2D:4D sex-specifically relates to life expectancy and suicide numbers on a national level (23 countries). The second-to-fourth finger length ratio (2D:4D) is an indication of prenatal sex hormone exposure, and has sex-specifically been associated with several lethal illnesses including ischemic heart disease, diverse cancers, and suicide. ![]()
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